Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3‐deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub‐study

AIM: Angiotensin receptor blockers (ARBs) reduce vascular complications in diabetes independently of blood pressure. Experimental studies suggested that ARBs may restore the detoxifying enzyme glyoxalase 1, thereby lowering dicarbonyls such as methylglyoxal. Human data on the effects of ARBs on plas...

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Detalles Bibliográficos
Autores principales: Piazza, M., Hanssen, N. M. J., Persson, F., Scheijen, J. L., van de Waarenburg, M. P. H., van Greevenbroek, M. M. J., Rossing, P., Hovind, P., Stehouwer, C. D. A., Parving, H‐H., Schalkwijk, C. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research: Treatment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451908/
https://www.ncbi.nlm.nih.gov/pubmed/32961617
http://dx.doi.org/10.1111/dme.14405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451908/
https://www.ncbi.nlm.nih.gov/pubmed/32961617
http://dx.doi.org/10.1111/dme.14405

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