The Triangulation WIthin a STudy (TWIST) framework for causal inference within pharmacogenetic research

In this paper we review the methodological underpinnings of the general pharmacogenetic approach for uncovering genetically-driven treatment effect heterogeneity. This typically utilises only individuals who are treated and relies on fairly strong baseline assumptions to estimate what we term the ‘g...

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Detalles Bibliográficos
Autores principales: Bowden, Jack, Pilling, Luke C, Türkmen, Deniz, Kuo, Chia-Ling, Melzer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452063/
https://www.ncbi.nlm.nih.gov/pubmed/34495953
http://dx.doi.org/10.1371/journal.pgen.1009783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452063/
https://www.ncbi.nlm.nih.gov/pubmed/34495953
http://dx.doi.org/10.1371/journal.pgen.1009783

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