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The Triangulation WIthin a STudy (TWIST) framework for causal inference within pharmacogenetic research
In this paper we review the methodological underpinnings of the general pharmacogenetic approach for uncovering genetically-driven treatment effect heterogeneity. This typically utilises only individuals who are treated and relies on fairly strong baseline assumptions to estimate what we term the ‘g...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452063/ https://www.ncbi.nlm.nih.gov/pubmed/34495953 http://dx.doi.org/10.1371/journal.pgen.1009783 |