SARS-CoV-2 Spike Protein Regulation of Angiotensin Converting Enzyme 2 and Tissue Renin-Angiotensin Systems: Influence of Biologic Sex

Angiotensin converting enzyme 2 (ACE2) is an enzyme that limits activity of the renin-angiotensin system (RAS) and also serves as a receptor for the SARS-CoV-2 Spike (S) protein. Binding of S protein to ACE2 causes internalization which activates local RAS. ACE2 is on the X chromosome and its expres...

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Detalles Bibliográficos
Autores principales: Ensor, Charles M., AlSiraj, Yasir, Shoemaker, Robin, Sturgill, Jamie, Keshavamurthy, Suresh, Gordon, Elizabeth M., Dong, Brittany E., Waters, Christopher, Cassis, Lisa A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452098/
https://www.ncbi.nlm.nih.gov/pubmed/34545369
http://dx.doi.org/10.1101/2021.09.14.460275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452098/
https://www.ncbi.nlm.nih.gov/pubmed/34545369
http://dx.doi.org/10.1101/2021.09.14.460275

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