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Increased Neutrophil-Subset Associated With Severity/Mortality In ARDS And COVID19-ARDS Expresses The Dual Endothelin-1/VEGFsignal-Peptide Receptor (DEspR): An Actionable Therapeutic Target

Neutrophil-mediated secondary tissue injury underlies acute respiratory distress syndrome (ARDS) and progression to multi-organ-failure (MOF) and death, processes linked to severe COVID19. This ‘innocent bystander’ tissue injury arises in dysregulated hyperinflammatory states from neutrophil functio...

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Detalles Bibliográficos
Autores principales: Herrera, Victoria L. M., Walkey, Allan J., Nguyen, Mai Q., Gromisch, Christopher M., Mosaddhegi, Julie Z., Gromisch, Matthew S., Jundi, Bakr, Lukassen, Soeren, Carstensen, Saskia, Denis, Ridiane, Belkina, Anna C., Baron, Rebecca M., Pinilla-Vera, Mayra, Muller, Meike, Kimberly, W. Taylor, Goldstein, Joshua N., Lehmann, Irina, Shih, Angela R., Ells, Roland, Levy, Bruce D., Rulz-Opazo, Nelson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452107/
https://www.ncbi.nlm.nih.gov/pubmed/34545358
http://dx.doi.org/10.21203/rs.3.rs-846250/v1