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Application of a dual mechanistic approach to support bilastine dose selection for older adults

The objective of this study was to evaluate bilastine dosing recommendations in older adults and overcome the limitation of insufficient data from phase I studies in this underrepresented population. This was achieved by integrating bilastine physicochemical, in vitro and in vivo data in young adult...

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Detalles Bibliográficos
Autores principales: Kim, Chaejin, Lo Re, Valentina, Rodriguez, Monica, Lukas, John C., Leal, Nerea, Campo, Cristina, García‐Bea, Aintzane, Suarez, Elena, Schmidt, Stephan, Vozmediano, Valvanera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452293/
https://www.ncbi.nlm.nih.gov/pubmed/34157202
http://dx.doi.org/10.1002/psp4.12671