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Application of a dual mechanistic approach to support bilastine dose selection for older adults
The objective of this study was to evaluate bilastine dosing recommendations in older adults and overcome the limitation of insufficient data from phase I studies in this underrepresented population. This was achieved by integrating bilastine physicochemical, in vitro and in vivo data in young adult...
Autores principales: | Kim, Chaejin, Lo Re, Valentina, Rodriguez, Monica, Lukas, John C., Leal, Nerea, Campo, Cristina, García‐Bea, Aintzane, Suarez, Elena, Schmidt, Stephan, Vozmediano, Valvanera |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452293/ https://www.ncbi.nlm.nih.gov/pubmed/34157202 http://dx.doi.org/10.1002/psp4.12671 |
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