A best practice framework for applying physiologically‐based pharmacokinetic modeling to pediatric drug development

Pediatric physiologically‐based pharmacokinetic (PBPK) models have broad application in the drug development process and are being used not only to project doses for clinical trials but increasingly to replace clinical studies. However, the approach has yet to become fully integrated in regulatory s...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, Trevor N., Small, Ben G., Berglund, Eva Gil, Rowland Yeo, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452294/
https://www.ncbi.nlm.nih.gov/pubmed/34288581
http://dx.doi.org/10.1002/psp4.12678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452294/
https://www.ncbi.nlm.nih.gov/pubmed/34288581
http://dx.doi.org/10.1002/psp4.12678

Ejemplares similares