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A best practice framework for applying physiologically‐based pharmacokinetic modeling to pediatric drug development
Pediatric physiologically‐based pharmacokinetic (PBPK) models have broad application in the drug development process and are being used not only to project doses for clinical trials but increasingly to replace clinical studies. However, the approach has yet to become fully integrated in regulatory s...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452294/ https://www.ncbi.nlm.nih.gov/pubmed/34288581 http://dx.doi.org/10.1002/psp4.12678 |