Cytochrome P450 2D6 genotype–phenotype characterization through population pharmacokinetic modeling of tedatioxetine

The cytochrome P450 (CYP) 2D6 enzyme exhibits large interindividual differences in metabolic activity. Patients are commonly assigned a CYP2D6 phenotype based on their CYP2D6 genotype, but there is a lack of consensus on how to translate genotypes into phenotypes, causing inconsistency in genotype‐b...

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Detalles Bibliográficos
Autores principales: Frederiksen, Trine, Areberg, Johan, Schmidt, Ellen, Stage, Tore Bjerregaard, Brøsen, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452298/
https://www.ncbi.nlm.nih.gov/pubmed/33932135
http://dx.doi.org/10.1002/psp4.12635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452298/
https://www.ncbi.nlm.nih.gov/pubmed/33932135
http://dx.doi.org/10.1002/psp4.12635

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