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Maturation of Purkinje cell firing properties relies on neurogenesis of excitatory neurons

Preterm infants that suffer cerebellar insults often develop motor disorders and cognitive difficulty. Excitatory granule cells, the most numerous neuron type in the brain, are especially vulnerable and likely instigate disease by impairing the function of their targets, the Purkinje cells. Here, we...

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Detalles Bibliográficos
Autores principales: van der Heijden, Meike E, Lackey, Elizabeth P, Perez, Ross, Ișleyen, Fatma S, Brown, Amanda M, Donofrio, Sarah G, Lin, Tao, Zoghbi, Huda Y, Sillitoe, Roy V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452305/
https://www.ncbi.nlm.nih.gov/pubmed/34542409
http://dx.doi.org/10.7554/eLife.68045