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Engineered models of the human heart: Directions and challenges

Human heart (patho)physiology is now widely studied using human pluripotent stem cells, but the immaturity of derivative cardiomyocytes has largely limited disease modeling to conditions associated with mutations in cardiac ion channel genes. Recent advances in tissue engineering and organoids have,...

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Detalles Bibliográficos
Autores principales: Stein, Jeroen M., Mummery, Christine L., Bellin, Milena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452488/
https://www.ncbi.nlm.nih.gov/pubmed/33338434
http://dx.doi.org/10.1016/j.stemcr.2020.11.013