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CHD4 ensures stem cell lineage fidelity during skeletal muscle regeneration

Regeneration of skeletal muscle requires resident stem cells called satellite cells. Here, we report that the chromatin remodeler CHD4, a member of the nucleosome remodeling and deacetylase (NuRD) repressive complex, is essential for the expansion and regenerative functions of satellite cells. We sh...

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Detalles Bibliográficos
Autores principales: Sreenivasan, Krishnamoorthy, Rodríguez-delaRosa, Alejandra, Kim, Johnny, Mesquita, Diana, Segalés, Jessica, Arco, Pablo Gómez-del, Espejo, Isabel, Ianni, Alessandro, Di Croce, Luciano, Relaix, Frederic, Redondo, Juan Miguel, Braun, Thomas, Serrano, Antonio L., Perdiguero, Eusebio, Muñoz-Cánoves, Pura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452531/
https://www.ncbi.nlm.nih.gov/pubmed/34450038
http://dx.doi.org/10.1016/j.stemcr.2021.07.022