Cargando…

Generation of pancreatic progenitors from human pluripotent stem cells by small molecules

Human pluripotent stem cell (hPSC)-derived pancreatic progenitors (PPs) provide promising cell therapies for type 1 diabetes. Current PP differentiation requires a high amount of Activin A during the definitive endoderm (DE) stage, making it economically difficult for commercial ventures. Here we id...

Descripción completa

Detalles Bibliográficos
Autores principales: Jiang, Yuqian, Chen, Chuanxin, Randolph, Lauren N., Ye, Songtao, Zhang, Xin, Bao, Xiaoping, Lian, Xiaojun Lance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452541/
https://www.ncbi.nlm.nih.gov/pubmed/34450037
http://dx.doi.org/10.1016/j.stemcr.2021.07.021