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Nucleotide proofreading functions by nematode RAD51 paralogs facilitate optimal RAD51 filament function

The RAD51 recombinase assembles as helical nucleoprotein filaments on single-stranded DNA (ssDNA) and mediates invasion and strand exchange with homologous duplex DNA (dsDNA) during homologous recombination (HR), as well as protection and restart of stalled replication forks. Strand invasion by RAD5...

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Detalles Bibliográficos
Autores principales: Špírek, Mário, Taylor, Martin R. G., Belan, Ondrej, Boulton, Simon J., Krejci, Lumir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452638/
https://www.ncbi.nlm.nih.gov/pubmed/34545070
http://dx.doi.org/10.1038/s41467-021-25830-x