Modular ketal-linked prodrugs and biomaterials enabled by organocatalytic transisopropenylation of alcohols

Isopropenyl ethers are critical intermediates for accessing medicinally valuable ketal-based prodrugs and biomaterials, but traditional approaches for the synthesis of isopropenyl ethers suffer from poor functional group compatibility and harsh reaction conditions. Here, we develop an organocatalyti...

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Detalles Bibliográficos
Autores principales: Yu, Na, Xu, Yang, Liu, Tao, Zhong, Haiping, Xu, Zunkai, Ji, Tianjiao, Zou, Hui, Mu, Jingqing, Chen, Ziqi, Liang, Xing-Jie, Shi, Linqi, Kohane, Daniel S., Guo, Shutao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452702/
https://www.ncbi.nlm.nih.gov/pubmed/34545089
http://dx.doi.org/10.1038/s41467-021-25856-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452702/
https://www.ncbi.nlm.nih.gov/pubmed/34545089
http://dx.doi.org/10.1038/s41467-021-25856-1

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