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Effects of apolipoprotein E isoform, sex, and diet on insulin BBB pharmacokinetics in mice

Age, apolipoprotein E (apoE) isoform, sex, and diet can independently affect the risk for the development of Alzheimer’s disease (AD). Additionally, synergy between some of these risk factors have been observed. However, the relation between the latter three risk factors has not been investigated. C...

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Detalles Bibliográficos
Autores principales: Rhea, Elizabeth M., Hansen, Kim, Pemberton, Sarah, Torres, Eileen Ruth S., Holden, Sarah, Raber, Jacob, Banks, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452709/
https://www.ncbi.nlm.nih.gov/pubmed/34545146
http://dx.doi.org/10.1038/s41598-021-98061-1