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7,8-dihydroxyflavone ameliorates motor deficits via regulating autophagy in MPTP-induced mouse model of Parkinson’s disease

Parkinson’s disease (PD) is a neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra and diminished dopamine content in the striatum. Recent reports show that 7,8-dihydroxyflavone (DHF), a TrkB agonist, attenuates the α-synuclein deposition and ameliorate...

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Detalles Bibliográficos
Autores principales: Zuo, Li, Dai, Chunfang, Yi, Lilin, Dong, Zhifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452727/
https://www.ncbi.nlm.nih.gov/pubmed/34545064
http://dx.doi.org/10.1038/s41420-021-00643-5