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Targeting the Lnc-OPHN1-5/androgen receptor/hnRNPA1 complex increases Enzalutamide sensitivity to better suppress prostate cancer progression

Long non-coding RNAs (lncRNAs) have been found to play critical roles in regulating gene expression, but their function in translational control is poorly understood. We found lnc-OPHN1-5, which lies close to the androgen receptor (AR) gene on chromosome X, increased prostate cancer (PCa) Enzalutami...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Sun, Yin, Huang, Chi-Ping, Luo, Jie, Zhang, Li, Meng, Jialin, Liang, Chaozhao, Chang, Chawnshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452728/
https://www.ncbi.nlm.nih.gov/pubmed/34545067
http://dx.doi.org/10.1038/s41419-021-03966-4