Cargando…

LncRNA PCBP1-AS1-mediated AR/AR-V7 deubiquitination enhances prostate cancer enzalutamide resistance

The refractory of castration-resistant prostate cancer (CRPC) is mainly reflected in drug resistance. The current research on the resistance mechanism of CRPC is still in its infancy. In this study, we revealed for the first time the key role of LncRNA PCBP1-AS1 in CRPC drug resistance. Through deta...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Boya, Zhang, Mingpeng, Shen, Chunyi, Liu, Guancong, Zhang, Fan, Hou, Jingyu, Yao, Weitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452729/
https://www.ncbi.nlm.nih.gov/pubmed/34545063
http://dx.doi.org/10.1038/s41419-021-04144-2