HIV reprograms host m(6)Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1

N(6),2′-O-dimethyladenosine (m(6)Am) is an abundant RNA modification located adjacent to the 5′-end of the mRNA 7-methylguanosine (m(7)G) cap structure. m(6)A methylation on 2′-O-methylated A at the 5′-ends of mRNAs is catalyzed by the methyltransferase Phosphorylated CTD Interacting Factor 1 (PCIF1...

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Detalles Bibliográficos
Autores principales: Zhang, Qiong, Kang, Yuqi, Wang, Shaobo, Gonzalez, Gwendolyn Michelle, Li, Wanyu, Hui, Hui, Wang, Yinsheng, Rana, Tariq M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452764/
https://www.ncbi.nlm.nih.gov/pubmed/34545078
http://dx.doi.org/10.1038/s41467-021-25683-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452764/
https://www.ncbi.nlm.nih.gov/pubmed/34545078
http://dx.doi.org/10.1038/s41467-021-25683-4

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