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Oncogenic signaling inhibits c-FLIP(L) expression and its non-apoptotic function during ECM-detachment

Inhibition of programmed cell death pathways is frequently observed in cancer cells where it functions to facilitate tumor progression. However, some proteins involved in the regulation of cell death function dichotomously to both promote and inhibit cell death depending on the cellular context. As...

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Detalles Bibliográficos
Autores principales: Tsegaye, Matyas Abel, He, Jianping, McGeehan, Kyle, Murphy, Ireland M., Nemera, Mati, Schafer, Zachary T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452765/
https://www.ncbi.nlm.nih.gov/pubmed/34545139
http://dx.doi.org/10.1038/s41598-021-97715-4