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Early Intervention via Stimulation of the Medial Septal Nucleus Improves Cognition and Alters Markers of Epileptogenesis in Pilocarpine-Induced Epilepsy

Over one-third of patients with temporal lobe epilepsy are refractory to medication. In addition, anti-epileptic drugs often exacerbate cognitive comorbidities. Neuromodulation is an FDA treatment for refractory epilepsy, but patients often wait >20 years for a surgical referral for resection or...

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Detalles Bibliográficos
Autores principales: Izadi, Ali, Schedlbauer, Amber, Ondek, Katelynn, Disse, Gregory, Ekstrom, Arne D., Cowen, Stephen L., Shahlaie, Kiarash, Gurkoff, Gene G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452867/
https://www.ncbi.nlm.nih.gov/pubmed/34557145
http://dx.doi.org/10.3389/fneur.2021.708957