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Efficient acquisition of tens of thousands of short tandem repeats in single-cell whole-genome-amplified DNA
Short tandem repeats (STRs) are highly abundant in the human genome, but existing approaches for accurate genotyping of STRs are limited. Here, we describe a protocol for duplex molecular inversion probes for high-throughput and cost-effective STR enrichment. We have successfully tested panels targe...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452885/ https://www.ncbi.nlm.nih.gov/pubmed/34585162 http://dx.doi.org/10.1016/j.xpro.2021.100828 |