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Efficient acquisition of tens of thousands of short tandem repeats in single-cell whole-genome-amplified DNA

Short tandem repeats (STRs) are highly abundant in the human genome, but existing approaches for accurate genotyping of STRs are limited. Here, we describe a protocol for duplex molecular inversion probes for high-throughput and cost-effective STR enrichment. We have successfully tested panels targe...

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Detalles Bibliográficos
Autores principales: Tao, Liming, Marx, Zipora, Raz, Ofir, Shapiro, Ehud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452885/
https://www.ncbi.nlm.nih.gov/pubmed/34585162
http://dx.doi.org/10.1016/j.xpro.2021.100828