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Comparison of 2-Hydroxyglutarate Detection With sLASER and MEGA-sLASER at 7T

The onco-metabolite 2-hydroxyglutarate (2HG), a biomarker of IDH-mutant gliomas, can be detected with (1)H MR spectroscopy ((1)H-MRS). Recent studies showed measurements of 2HG at 7T with substantial gain in signal to noise ratio (SNR) and spectral resolution, offering higher specificity and sensiti...

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Detalles Bibliográficos
Autores principales: Shams, Zahra, van der Kemp, Wybe J. M., Emir, Uzay, Dankbaar, Jan Willem, Snijders, Tom J., de Vos, Filip Y. F., Klomp, Dennis W. J., Wijnen, Jannie P., Wiegers, Evita C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452903/
https://www.ncbi.nlm.nih.gov/pubmed/34557149
http://dx.doi.org/10.3389/fneur.2021.718423