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Noggin Overexpression Impairs the Development of Muscles, Tendons, and Aponeurosis in Soft Palates by Disrupting BMP-Smad and Shh-Gli1 Signaling

The roles of bone morphogenetic protein (BMP) signaling in palatogenesis were well documented in the developing hard palate; however, little is known about how BMP signaling regulates the development of soft palate. In this study, we overexpressed Noggin transgene via Osr2-cre(KI) allele to suppress...

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Detalles Bibliográficos
Autores principales: Deng, Jiamin, Wang, Shangqi, Li, Nan, Chen, Xiaoyan, Wang, Biying, Liu, Han, Zhu, Lei, Cong, Wei, Xiao, Jing, Liu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453081/
https://www.ncbi.nlm.nih.gov/pubmed/34557486
http://dx.doi.org/10.3389/fcell.2021.711334