Generation of a GLO-2 deficient mouse reveals its effects on liver carbonyl and glutathione levels

OBJECTIVE: Hydroxyacylglutathione hydrolase (aka as GLO-2) is a component of the glyoxalase pathway involved in the detoxification of the reactive oxoaldehydes, glyoxal and methylglyoxal. These reactive metabolites have been linked to a variety of pathological conditions, including diabetes, cancer...

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Detalles Bibliográficos
Autores principales: Li, Xingsheng, Fargue, Sonia, Challa, Anil Kumar, Poore, William, Knight, John, Wood, Kyle D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453187/
https://www.ncbi.nlm.nih.gov/pubmed/34584990
http://dx.doi.org/10.1016/j.bbrep.2021.101138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453187/
https://www.ncbi.nlm.nih.gov/pubmed/34584990
http://dx.doi.org/10.1016/j.bbrep.2021.101138

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