Increasing the heterologous production of spinosad in Streptomyces albus J1074 by regulating biosynthesis of its polyketide skeleton

Spinosyns are natural broad-spectrum biological insecticides with a double glycosylated polyketide structure that are produced by aerobic fermentation of the actinomycete, Saccharopolyspora spinosa. However, their large-scale overproduction is hindered by poorly understood bottlenecks in optimizing...

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Detalles Bibliográficos
Autores principales: An, Ziheng, Tao, Hui, Wang, Yong, Xia, Bingqing, Zou, Yang, Fu, Shuai, Fang, Fang, Sun, Xiao, Huang, Renqiong, Xia, Yao, Deng, Zixin, Liu, Ran, Liu, Tiangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453208/
https://www.ncbi.nlm.nih.gov/pubmed/34584996
http://dx.doi.org/10.1016/j.synbio.2021.09.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453208/
https://www.ncbi.nlm.nih.gov/pubmed/34584996
http://dx.doi.org/10.1016/j.synbio.2021.09.008

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