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A Universal Peptide Matrix Interactomics Approach to Disclose Motif-Dependent Protein Binding

Protein–protein interactions mediated by intrinsically disordered regions are often based on short linear motifs (SLiMs). SLiMs are implicated in signal transduction and gene regulation yet remain technically laborious and notoriously challenging to study. Here, we present an optimized method for a...

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Detalles Bibliográficos
Autores principales: Ramberger, Evelyn, Suarez-Artiles, Lorena, Perez-Hernandez, Daniel, Haji, Mohamed, Popp, Oliver, Reimer, Ulf, Leutz, Achim, Dittmar, Gunnar, Mertins, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453223/
https://www.ncbi.nlm.nih.gov/pubmed/34391889
http://dx.doi.org/10.1016/j.mcpro.2021.100135