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β-Hydroxybutyrate Mitigated Heart Failure with Preserved Ejection Fraction by Increasing Treg Cells via Nox2/GSK-3β
BACKGROUND: This study was designed to investigate the cardioprotective role of β-hydroxybutyrate (BHB) in heart failure with preserved ejection fraction (HFpEF) and the underlying mechanism. METHODS: A two-hit model with a high-fat diet (HFD) and N(ω)-nitrol-arginine methyl ester (L-NAME) was used...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453303/ https://www.ncbi.nlm.nih.gov/pubmed/34557014 http://dx.doi.org/10.2147/JIR.S331320 |