β-Hydroxybutyrate Mitigated Heart Failure with Preserved Ejection Fraction by Increasing Treg Cells via Nox2/GSK-3β

BACKGROUND: This study was designed to investigate the cardioprotective role of β-hydroxybutyrate (BHB) in heart failure with preserved ejection fraction (HFpEF) and the underlying mechanism. METHODS: A two-hit model with a high-fat diet (HFD) and N(ω)-nitrol-arginine methyl ester (L-NAME) was used...

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Detalles Bibliográficos
Autores principales: Liao, Shengen, Tang, Yuan, Yue, Xin, Gao, Rongrong, Yao, Wenming, Zhou, Yanli, Zhang, Haifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453303/
https://www.ncbi.nlm.nih.gov/pubmed/34557014
http://dx.doi.org/10.2147/JIR.S331320

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