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Carbon-Ion Beam Irradiation and the miR-200c Mimic Effectively Eradicate Pancreatic Cancer Stem Cells Under in vitro and in vivo Conditions

PURPOSE: The study investigated the molecular mechanisms that killed pancreatic cancer cells, including cancer stem cells (CSCs), by carbon ion beam irradiation alone or in combination with miRNA-200c under in vitro and in vivo conditions. METHODS: Human pancreatic cancer (PC) cells, PANC1 and PK45,...

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Detalles Bibliográficos
Autores principales: Sai, Sei, Kim, Eun Ho, Koom, Woong Sub, Vares, Guillaume, Suzuki, Masao, Yamada, Shigeru, Hayashi, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453446/
https://www.ncbi.nlm.nih.gov/pubmed/34556996
http://dx.doi.org/10.2147/OTT.S311567