Cargando…

OFF-State-Specific Inhibition of the Proprotein Convertase Furin

[Image: see text] The pro-protein convertase furin is a highly specific serine protease involved in the proteolytic maturation of many proteins in the secretory pathway. It also activates surface proteins of many viruses including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Fur...

Descripción completa

Detalles Bibliográficos
Autores principales: Dahms, Sven O., Haider, Tanja, Klebe, Gerhard, Steinmetzer, Torsten, Brandstetter, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453481/
https://www.ncbi.nlm.nih.gov/pubmed/34415722
http://dx.doi.org/10.1021/acschembio.1c00411