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Reconstitution and Structural Analysis of a HECT Ligase-Ubiquitin Complex via an Activity-Based Probe

[Image: see text] Ubiquitin activity-based probes have proven invaluable in elucidating structural mechanisms in the ubiquitin system by stabilizing transient macromolecular complexes of deubiquitinases, ubiquitin-activating enzymes, and the assemblies of ubiquitin-conjugating enzymes with ubiquitin...

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Detalles Bibliográficos
Autores principales: Nair, Rahul M., Seenivasan, Ayshwarya, Liu, Bing, Chen, Dan, Lowe, Edward D., Lorenz, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453484/
https://www.ncbi.nlm.nih.gov/pubmed/34403242
http://dx.doi.org/10.1021/acschembio.1c00433