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Reconstitution and Structural Analysis of a HECT Ligase-Ubiquitin Complex via an Activity-Based Probe
[Image: see text] Ubiquitin activity-based probes have proven invaluable in elucidating structural mechanisms in the ubiquitin system by stabilizing transient macromolecular complexes of deubiquitinases, ubiquitin-activating enzymes, and the assemblies of ubiquitin-conjugating enzymes with ubiquitin...
Autores principales: | Nair, Rahul M., Seenivasan, Ayshwarya, Liu, Bing, Chen, Dan, Lowe, Edward D., Lorenz, Sonja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453484/ https://www.ncbi.nlm.nih.gov/pubmed/34403242 http://dx.doi.org/10.1021/acschembio.1c00433 |
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