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Early Oxidative Transformations During the Biosynthesis of Terrein and Related Natural Products

The mycotoxin terrein is derived from the C(10)‐precursor 6‐hydroxymellein (6‐HM) via an oxidative ring contraction. Although the corresponding biosynthetic gene cluster (BGC) has been identified, details of the enzymatic oxidative transformations are lacking. Combining heterologous expression and i...

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Detalles Bibliográficos
Autores principales: Kahlert, Lukas, Bernardi, Darlon, Hauser, Maurice, Ióca, Laura P., Berlinck, Roberto G. S., Skellam, Elizabeth J., Cox, Russell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453496/
https://www.ncbi.nlm.nih.gov/pubmed/34114710
http://dx.doi.org/10.1002/chem.202101447

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