The T‐type calcium channel antagonist, Z944, reduces spinal excitability and pain hypersensitivity

BACKGROUND AND PURPOSE: T‐type voltage‐gated calcium channels are an emerging therapeutic target for neurological disorders including epilepsy and pain. Inhibition of T‐type channels reduces the excitability of peripheral nociceptive sensory neurons and reverses pain hypersensitivity in male rodent...

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Detalles Bibliográficos
Autores principales: Harding, Erika K., Dedek, Annemarie, Bonin, Robert P., Salter, Michael W., Snutch, Terrance P., Hildebrand, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453510/
https://www.ncbi.nlm.nih.gov/pubmed/33871884
http://dx.doi.org/10.1111/bph.15498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453510/
https://www.ncbi.nlm.nih.gov/pubmed/33871884
http://dx.doi.org/10.1111/bph.15498

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