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The T‐type calcium channel antagonist, Z944, reduces spinal excitability and pain hypersensitivity
BACKGROUND AND PURPOSE: T‐type voltage‐gated calcium channels are an emerging therapeutic target for neurological disorders including epilepsy and pain. Inhibition of T‐type channels reduces the excitability of peripheral nociceptive sensory neurons and reverses pain hypersensitivity in male rodent...
Autores principales: | Harding, Erika K., Dedek, Annemarie, Bonin, Robert P., Salter, Michael W., Snutch, Terrance P., Hildebrand, Michael E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453510/ https://www.ncbi.nlm.nih.gov/pubmed/33871884 http://dx.doi.org/10.1111/bph.15498 |
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