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Elovl5 is required for proper action potential conduction along peripheral myelinated fibers

Elovl5 elongates fatty acids with 18 carbon atoms and in cooperation with other enzymes guarantees the normal levels of very long‐chain fatty acids, which are necessary for a proper membrane structure. Action potential conduction along myelinated axons depends on structural integrity of myelin, whic...

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Detalles Bibliográficos
Autores principales: Hoxha, Eriola, Balbo, Ilaria, Parolisi, Roberta, Audano, Matteo, Montarolo, Francesca, Ravera, Francesco, Guglielmotto, Michela, Muratori, Luisa, Raimondo, Stefania, DiGregorio, Eleonora, Buffo, Annalisa, Brusco, Alfredo, Borroni, Barbara, Mitro, Nico, Caruso, Donatella, Tempia, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453547/
https://www.ncbi.nlm.nih.gov/pubmed/34139039
http://dx.doi.org/10.1002/glia.24048