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A Mild and Highly Diastereoselective Preparation of N-Alkenyl-2-Pyridones via 2-Halopyridinium Salts and Aldehydes

[Image: see text] An experimentally simple one-pot preparation of N-alkenyl-2-pyridones is reported. The reaction features mild conditions using readily available 2-halopyridinium salts and aldehydes. N-Alkenyl-2-pyridone formation proceeds with high diastereoselectivity, and a wide range of aldehyd...

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Detalles Bibliográficos
Autores principales: Shivers, Grant N., Pigge, F. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453634/
https://www.ncbi.nlm.nih.gov/pubmed/34464531
http://dx.doi.org/10.1021/acs.joc.1c01566