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The Effects of NPY1 Receptor Antagonism on Intervertebral Disc and Bone Changes in Ovariectomized Rats

STUDY DESIGN: Basic science. OBJECTIVE: To compare the effects of a neuropeptide Y1 receptor antagonist (NPY-1RA) to estrogen on maintaining vertebral bone microarchitecture and disc height in a rat model of menopause. METHODS: This study was an institutional animal care approved randomized control...

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Detalles Bibliográficos
Autores principales: Tucci, Michelle, Wilson, Gerri A., McGuire, Robert, Benghuzzi, Hamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453679/
https://www.ncbi.nlm.nih.gov/pubmed/32748636
http://dx.doi.org/10.1177/2192568220939908