Activated microglia do not increase 18 kDa translocator protein (TSPO) expression in the multiple sclerosis brain

To monitor innate immune responses in the CNS, the 18 kDa Translocator protein (TSPO) is a frequently used target for PET imaging. The frequent assumption that increased TSPO expression in the human CNS reflects pro‐inflammatory activation of microglia has been extrapolated from rodent studies. Howe...

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Detalles Bibliográficos
Autores principales: Nutma, Erik, Gebro, Emeline, Marzin, Manuel C., van der Valk, Paul, Matthews, Paul M., Owen, David R., Amor, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453709/
https://www.ncbi.nlm.nih.gov/pubmed/34145928
http://dx.doi.org/10.1002/glia.24052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453709/
https://www.ncbi.nlm.nih.gov/pubmed/34145928
http://dx.doi.org/10.1002/glia.24052

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