Intratympanic Lipopolysaccharide Elevates Systemic Fluorescent Gentamicin Uptake in the Cochlea

OBJECTIVES/HYPOTHESIS: Lipopolysaccharide (LPS), a key component of bacterial endotoxins, activates macrophages and triggers the release of inflammatory cytokines in mammalian tissues. Recent studies have shown that intratympanic injection of LPS simulates acute otitis media (AOM) and results in mor...

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Detalles Bibliográficos
Autores principales: Chai, Yongchuan, He, Weiwei, Yang, Weiqiang, Hetrick, Alisa P., Gonzalez, Jessica G., Sargsyan, Liana, Wu, Hao, Jung, Timothy T. K., Li, Hongzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Otology‐Neurotology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453712/
https://www.ncbi.nlm.nih.gov/pubmed/33956344
http://dx.doi.org/10.1002/lary.29610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453712/
https://www.ncbi.nlm.nih.gov/pubmed/33956344
http://dx.doi.org/10.1002/lary.29610

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