Population Pharmacokinetic Modeling and Simulations of Imipenem in Burn Patients With and Without Continuous Venovenous Hemofiltration in the Military Health System

Continuous venovenous hemofiltration (CVVH) is a life‐sustaining procedure in patients with severe burns and acute kidney injury. Physiologic changes from burn injury and use of CVVH may alter imipenem pharmacokinetics (PK). We aimed to compare imipenem clearance (CL) in burn patients with and witho...

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Detalles Bibliográficos
Autores principales: Por, Elaine D., Akers, Kevin S., Chung, Kevin K., Livezey, Jeffrey R., Selig, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Pharmacometrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453752/
https://www.ncbi.nlm.nih.gov/pubmed/33811332
http://dx.doi.org/10.1002/jcph.1865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453752/
https://www.ncbi.nlm.nih.gov/pubmed/33811332
http://dx.doi.org/10.1002/jcph.1865

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