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Comprehensive Allele Genotyping in Critical Pharmacogenes Reduces Residual Clinical Risk in Diverse Populations

Genomic‐guided pharmaceutical prescribing is increasingly recognized as an important clinical application of genetics. Accurate genotyping of pharmacogenomic (PGx) genes can be difficult, owing to their complex genetic architecture involving combinations of single‐nucleotide polymorphisms and struct...

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Detalles Bibliográficos
Autores principales: Luo, Shishi, Jiang, Ruomu, Grzymski, Joseph J., Lee, William, Lu, James T., Washington, Nicole L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453755/
https://www.ncbi.nlm.nih.gov/pubmed/33930192
http://dx.doi.org/10.1002/cpt.2279