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Human transitional and IgM(low) mature naïve B cells preserve permissive B‐cell receptors

The level of immunoglobulin M (IgM) displayed on the surface of peripheral blood B cells exhibits a broad dynamic range and has been associated with both development and selection. To determine whether IgM surface expression associates with distinct immunoglobulin heavy‐chain (IGH) repertoire proper...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiguo, Jara, Christopher J, Singh, Mandeep, Xu, Huji, Goodnow, Christopher C, Jackson, Katherine JL, Reed, Joanne H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453828/
https://www.ncbi.nlm.nih.gov/pubmed/33988890
http://dx.doi.org/10.1111/imcb.12478