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Interleukin‐1β exacerbates disease and is a potential therapeutic target to reduce pulmonary inflammation during severe influenza A virus infection
Hyperinflammatory responses including the production of NLRP3‐dependent interleukin (IL)‐1β is a characteristic feature of severe and fatal influenza A virus (IAV) infections. The NLRP3 inflammasome has been shown to play a temporal role during severe IAV immune responses, with early protective and...
Autores principales: | Bawazeer, Abdulah OS, Rosli, Sarah, Harpur, Christopher M, Docherty, Callum AH, Mansell, Ashley, Tate, Michelle D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453884/ https://www.ncbi.nlm.nih.gov/pubmed/33834544 http://dx.doi.org/10.1111/imcb.12459 |
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