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HMGB1 promotes CXCL12‐dependent egress of murine B cells from Peyer's patches in homeostasis

High mobility group box‐1 protein (HMGB1) is an alarmin that, once released, promotes inflammatory responses, alone and as a complex with the chemokine CXCL12. Here, we report that the HMGB1–CXCL12 complex plays an essential role also in homeostasis by controlling the migration of B lymphocytes. We...

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Detalles Bibliográficos
Autores principales: Spagnuolo, Lorenzo, Puddinu, Viola, Boss, Noémie, Spinetti, Thibaud, Oberson, Anne, Widmer, Jerome, Mottas, Inès, Hotz, Christian, Bianchi, Marco E., Uguccioni, Mariagrazia, Bourquin, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453951/
https://www.ncbi.nlm.nih.gov/pubmed/34060652
http://dx.doi.org/10.1002/eji.202049120