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Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA

BACKGROUND: The liver plays a major role in the metabolic activation of xenobiotics (drugs, chemicals such as pollutants, pesticides, food additives...). Among environmental contaminants of concern, heterocyclic aromatic amines (HAA) are xenobiotics classified by IARC as possible or probable carcino...

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Detalles Bibliográficos
Autores principales: Conan, Mael, Théret, Nathalie, Langouet, Sophie, Siegel, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454073/
https://www.ncbi.nlm.nih.gov/pubmed/34548010
http://dx.doi.org/10.1186/s12859-021-04363-6