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Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
BACKGROUND: The liver plays a major role in the metabolic activation of xenobiotics (drugs, chemicals such as pollutants, pesticides, food additives...). Among environmental contaminants of concern, heterocyclic aromatic amines (HAA) are xenobiotics classified by IARC as possible or probable carcino...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454073/ https://www.ncbi.nlm.nih.gov/pubmed/34548010 http://dx.doi.org/10.1186/s12859-021-04363-6 |